The tissue-engineered cartilage bioreactor simulates the in vivo dynamic hydrostatic-pressure environment of cartilage. It applies hydrostatic stress at different frequencies and magnitudes to dynamically construct human cartilage tissue. Hydrostatic-pressure frequency and magnitude and medium flow can be adjusted, multiple cartilage tissues can be cultured simultaneously, and fully sealed culture prevents contamination of chondrocyte cultures.

A dynamic hydrostatic-pressure environment plays an important role in chondrocyte culture. When tissue-engineering methods combine chondrocytes with biodegradable materials to construct tissue-engineered cartilage, static culture is usually used. This makes cartilage tissue constructed in vitro prone to defects such as hollow regions, and its mechanical properties differ greatly from those of normal cartilage, preventing it from meeting clinical transplantation requirements. Currently reported hydrostatic-pressure environments are not enclosed and have difficulty creating a dynamic hydrostatic-pressure culture environment, resulting in restricted culture duration and many other shortcomings.Tissue-Engineered Cartilage BioreactorIt simulates the in vivo dynamic hydrostatic-pressure mechanical environment of cartilage. It applies hydrostatic stress at different frequencies and magnitudes to dynamically construct human cartilage tissue. Hydrostatic-pressure frequency and magnitude and medium flow can be adjusted, multiple cartilage tissues can be cultured simultaneously, and fully sealed culture prevents contamination of chondrocyte cultures.

1、Tissue-Engineered Cartilage BioreactorMain functions:

(1) Creates a hydrostatic-pressure–perfusion culture environment;          

(2) Cultures tissue-engineered cartilage, auricular cartilage, cartilage sheets, and other tissues;

(3) Uses a modular structural design;

(4) Collects data and performs mechanical analysis for all culture parameters.

2. Technical parameters:

(1) Hydrostatic-pressure range: 1–0.4 MPa;

(2) Perfusion flow: 0–20 mL/min, adjustable;

(3) Frequency-control range: 0–10 Hz;

(4) Supply voltage: AC220V±10%/50Hz±2%;

(5) Output power: 100 W;

(6) Overall dimensions (mm): 450 × 450 × 500;

(7) Culture capacity: 1 unit.

3. This product has received a Chinese invention patent grant:patentNo. ZL201510760414.9.

4. After-sales service and training:

(1) Free delivery to the user's address and free on-site installation and commissioning. From the date on which installation and commissioning pass user acceptance, the warranty period is one year, with all repairs free during the warranty period.

(2) During on-site installation and commissioning, technical staff train operators, with no limit on the number of trainees, until users can operate and perform routine maintenance independently.

(3) Repair response time ≤2 hours; proposed solution ≤24 hours; on-site technical support ≤48 hours.