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Hydrostatic Pressure Bioreactor for Cartilage Tissue Engineering

The cartilage tissue-engineering bioreactor simulates dynamic hydrostatic pressure conditions in vivo.

It applies pressure at adjustable magnitudes and frequencies to support the formation of engineered human cartilage.

Pressure, frequency, and medium flow can be adjusted, and multiple constructs can be cultured in an enclosed system designed to reduce contamination.

Model:BQ-1800

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+86-0571-85236562(Currently available in Chinese only)

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Product introduction

Product Specifications

Application AreasHealthcare, environmental protection, biotechnology, pharmaceuticals and biopharmaceuticals, general applications
Hydrostatic pressure range0–1 MPa
Frequency-control range0-10 Hz
Culture capacity1–4 specimens
Power supplyAC220 V±10%/50 Hz±2%
Output power100 W
External dimensions (mm)450×450×500

Product Overview

Dynamic hydrostatic pressure is important in chondrocyte culture.

When chondrocytes are combined with biodegradable materials to engineer cartilage, static culture can produce defects such as hollow regions and mechanical properties far below those of native cartilage, limiting suitability for transplantation.

Some reported pressure-culture systems lack an enclosed environment or sustained dynamic hydrostatic loading, which can limit culture duration and performance.

The cartilage tissue-engineering bioreactor simulates dynamic hydrostatic pressure conditions in vivo.

It applies pressure at adjustable magnitudes and frequencies to support the formation of engineered human cartilage.

Pressure, frequency, and medium flow can be adjusted, and multiple constructs can be cultured in an enclosed system designed to reduce contamination.

1. Main Functions:

  • (1) Combines hydrostatic pressure stimulation with perfusion culture.
  • (2) Cultures engineered cartilage tissue, human auricular cartilage, cartilage sheets, and related constructs.
  • (3) Modular design.
  • (4) Data acquisition for culture parameters and mechanical analysis.

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2. Technical Specifications:

  • (1) Hydrostatic pressure range: 0–1 MPa.
  • (2) Perfusion flow rate: 0–20 mL/min, adjustable.
  • (3) Frequency-control range: 0–10 Hz.
  • (4) Power supply: 220 V AC ±10% / 50 Hz ±2%.
  • (5) Output power: 100 W.
  • (6) External dimensions (mm): 450 × 450 × 500.
  • (7) Culture capacity: 1 unit.
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