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Biomechanical Bioreactor for Corneal Tissue Engineering

Biomechanical Bioreactor for Corneal Tissue Engineering

The biomechanical bioreactor for corneal tissue engineering simulates the mechanical environment of the eye for in vitro culture of multiple engineered corneas, with real-time assessment of corneal stromal transparency.

It is suitable for product development, production, and quality testing at hospitals, universities, research institutes, and biomedical engineering companies.

Model:BQ-2800

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+86-0571-85236562(Currently available in Chinese only)

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Product Specifications

Application AreasHealthcare, environmental protection, pharmaceuticals and biopharmaceuticals, general applications

Product Overview

The biomechanical bioreactor for corneal tissue engineering simulates the mechanical environment of the eye for in vitro culture of multiple engineered corneas, with real-time assessment of corneal stromal transparency.

It is suitable for product development, production, and quality testing at hospitals, universities, research institutes, and biomedical engineering companies.

1. Main Functions:

  • (1) Simulates the corneal biomechanical environment for dynamic culture of corneal endothelial cells combined with biomaterials.
  • (2) Provides perfusion to maintain an adequate nutrient supply.
  • (3) Supports construction of curved corneal shapes resembling natural corneal refractive geometry.
  • (4) 8 culture units can operate simultaneously and independently.
  • (5) Modular design for stable, reliable operation.
  • (6) Culture parameters can be set for each unit.

2. Technical Specifications:

  • (1) Applied force range: 1–50 N.
  • (2) Perfusion flow rate: 0–20 mL/min, adjustable.
  • (3) Culture capacity: 8 specimens.
  • (4) Frequency-control range: 0–1 Hz.
  • (5) Power supply: 220 V AC ±10% / 50 Hz ±2%.
  • (6) Output power: 100 W.

3. Application Examples:

  • (1) Combined culture of decellularized porcine corneal matrix and endothelial cells.

Biomechanical Bioreactor for Corneal Tissue EngineeringBiomechanical Bioreactor for Corneal Tissue EngineeringBiomechanical Bioreactor for Corneal Tissue Engineering

  • (2) In vitro construction of viable corneas.

Corneal Culture Incubator and Viable Tissue-Engineered Cornea

Microscopy
Primary corneal stromal cells (10×)
Corneal stroma, H&E staining (10×)
Corneal stroma, TEM (8 weeks; 3000×)
Culture and measurement
Tissue-engineered corneal stroma (6 weeks)
Tissue-engineered cornea transparency measurement system
In vitro culture incubator for tissue-engineered corneas

H&E: hematoxylin and eosin staining; TEM: transmission electron microscopy.

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