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Culture Results of Tissue-Engineered Blood Vessels

Pulsatile Bioreactor for Vascular Tissue Engineering

The pulsatile vascular tissue-engineering bioreactor simulates in vivo vascular hydrodynamics, with adjustable pulsation frequency and intensity for dynamic culture of engineered blood vessels of different inner diameters.

It is suitable for product development, production, and quality testing at hospitals, universities, research institutes, and biomedical engineering companies.

Model:BQ-2280

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Product Specifications

Application AreasEnvironmental protection, biotechnology, pharmaceuticals and biopharmaceuticals, general applications

Product Overview

  The vascular tissue-engineering bioreactor simulates in vivo vascular hydrodynamics, with adjustable pulsation frequency and intensity for dynamic culture of engineered blood vessels of different inner diameters.

It is suitable for product development, production, and quality testing at hospitals, universities, research institutes, and biomedical engineering companies.

1. Main Functions

  • (1)Simulates vascular hydrodynamic conditions in vivo to construct tissue-engineered blood vessels.
  • (2)Supports construction of small blood vessels with an inner diameter of 2 mm as well as cardiac valves and related tissues;
  • (3)Modular design allows independent operation of individual units, reducing cross-contamination.

2. Technical Specifications

  • (1)Pulsatile pressure range: 0-300 mmHg
  • (2)Frequency: 0-3 Hz
  • (3)Inner diameter of engineered tissue ( Ø6 mm-1.5 mm )
  • (4)Compliance: 0-10%
  • (5)Power supply: AC220 V ± 10%/50 Hz ± 2%
  • (6)Output power: 200 W
  • (7)Culture capacity: 8 units

3. Application Examples

  • (1) Construction of tissue-engineered blood vessels with an inner diameter of 6 mm.

Culture Results of Tissue-Engineered Blood Vessels

Dynamic culture group
Front view
Side view
H&E staining
Static culture group
Front view
Side view
H&E staining

Hematoxylin and eosin (H&E) staining

  • (2) Use of adipose-derived stem cells to construct small blood vessels with an inner diameter of 2 mm.

Tissue-Engineered Blood Vessels Constructed Using ADSCs

4 weeks of culture
500×1000×

Scanning electron microscopy (SEM)

  • (3) Use of bone-marrow stromal stem cells to construct small blood vessels with an inner diameter of 2 mm.

Gross Morphology of Tissue-Engineered Blood Vessels Constructed Using hBMSCs

4 weeks of culture

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