1. Regulates mechanosignaling pathways through mechanical stimulation to maintain stem-cell
self-renewal and inhibit differentiation.
2. Avoids introducing microcarriers, reducing the risks associated with returning stem cells
to the body.
3. Produces cleaner cell supernatant, providing favorable conditions for subsequent exosome
purity.
4. Mechanical stimulation can promote and increase stem-cell exosome yield.
5. Mechanical stimulation can regulate exosome composition and function.

1. Regulates mechanosignaling pathways through mechanical stimulation to maintain stem-cell

self-renewal and inhibit differentiation.

2. Avoids introducing microcarriers, reducing the risks associated with returning stem cells

to the body.

3. Produces cleaner cell supernatant, providing favorable conditions for subsequent exosome

purity.

4. Mechanical stimulation can promote and increase stem-cell exosome yield.

5. Mechanical stimulation can regulate exosome composition and function.

System advantages:

◆Regulates mechanosignaling pathways through mechanical stimulation to maintain stem-cell self-renewal and inhibit differentiation

◆Low-intensity stimulation of specific types maintains the stemness of mesenchymal and embryonic stem cells

◆Targeted regulation of signaling pathways enables stem-cell culture for specific requirements

◆Avoids introducing microcarriers, reducing the risks associated with returning stem cells to the body

◆Produces cleaner cell supernatant, providing favorable conditions for subsequent exosome purity

◆Mechanical stimulation can promote and increase stem-cell exosome yield

◆Mechanical stimulation can regulate exosome composition and function, such as enhancing tissue-repair and anti-inflammatory activity